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HspQ protein domain : ウィキペディア英語版 | HspQ protein domain
In molecular biology, YccV protein domain is also, alternatively named, Heat shock protein HspQ. This entry describes the small protein from ''Escherichia coli'' YccV and its homologs in other Proteobacteria. YccV is now described as a hemimethylated DNA binding protein. The model entry describes a protein domain in longer eukaryotic proteins. ==Function==
HspQ is involved in the degradation of certain denaturated proteins, including DnaA, during Heat shock stress.〔 〕 HspQ (YccV like protein domain) is a hemimethylated DNA-binding protein. It has been thought to negatively regulate dnaA gene expression when its promoter region is either methylated or hemimethylated. This could occurs through binding of YccV itself to fully or hemimethylated DNA.〔 In addition, studies have identified the ''yccV'' gene as one of three insertion sites in mini-Tn10 which suppress dnaA46 thermosensitivity.
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